Enzyme Discovery
Novel enzymes unlock intricate reactions to produce unique molecules in the production of Active Pharmaceutical Ingredients (APIs)
Why novel enzymes?
- Innovation - A uniquely developed enzyme offers a host of advantages. The activity and specificity of an enzyme can be developed to meet the distinct substrate, process and end product requirements. Developing novel enzymes enables innovation for the next generation of vaccines, medicines and pharmaceuticals.
- Intellectual Property & FTO - Developing novel enzymes can allow customers to protect their R&D and innovations through intellectual property. A novel enzyme, e.g. defined by an identity of less than 90-95% to known enzymes, with inventive properties can often be protected to exclude competition from their innovative space.
- Efficiencies - Enzymes are intricate proteins, depending on the process and intended application there are functionalities that can be improved through enzyme discovery and engineering. Developing a novel enzyme can improve the efficiency of the enzyme in application, the increased productivity or yields can make significant advantages when applied at commercial scales.
Proprietary digital database for fast enzyme & protein discovery
- Database - Access natures diversity through our metagenomic database harbouring 99.8% novel sequences
- Design - Explore beyond nature by AI-drive enzyme design.
- Discover - Discover and identify tailored enzymes leveraging bioinformatics and AI
For more information on the technologies and techniques available for discovering novel enzymes for your application, click below:
Protein Engineering
Protein engineering is the technique of developing proteins with increased added value through making alterations to its amino acid sequence improving its functionality or suitability to a given application or process. Focussing on rational design, we utilise bioinformatics guided approaches to optimise enzymes to ensure a fast and cost effective process for developing a novel enzyme designed for success in your application.
Entire protein engineering projects: We handle the entire package - from protein design to in-depth characterisation of enzyme variants.
Not limited to one method: We combine different effective methods and use a solution-oriented engineering approach with the application goal firmly in mind.
Difficult challenges welcome: We work on standard enzyme optimisation projects but also specialise in “difficult enzymes”, e.g. transporters and enzyme cascades that call for more than just a standard assay.
For more information on how protein engineering can be incorporated into your enzyme development projects, click below:
